In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Financial markets are often seen as chaotic and unpredictable. Every day, traders around the world buy shares and sell assets in a whirlwind of activity. It looks like a system of total randomness—but ...

CLEVELAND, Ohio -- Monty Python’s “Spamalot” is embarking on a quest to hit more than two dozen cities over the next nine months, and Cleveland is the first stop. Based on the cult comedy classic ...

CLEVELAND, Ohio -- Fifty years after “Monty Python and the Holy Grail,” Eric Idle never thought he’d still be talking about the cult classic film, much less a musical inspired by it. But here we are, ...

Just because you are paranoid doesn’t mean people aren’t out to get you. Do you think your soldering iron is after you? Well, [nanofix] asks (and answers): Is My Soldering Iron Dangerous? He has a ...

Years ago, no math education was complete without understanding how to compute a square root. Today, you are probably just reaching for a calculator, or if you are writing a program, you’ll probably ...

Understanding plant root systems is vital to improving crop productivity and climate adaptation, yet their complex underground structures remain difficult to characterize. Conventional imaging methods ...

Learn the Adagrad optimization algorithm, how it works, and how to implement it from scratch in Python for machine learning models. #Adagrad #Optimization #Python Here Are the States That Won't Tax ...

grpfc attempts to find all the zeros and poles of a complex valued function with complex arguments in a fixed region. These types of problems are frequently encountered in electromagnetics, but the ...

Whether you’re solving geometry problems, handling scientific computations, or processing data arrays, calculating square roots in Python is a fundamental task. Python offers multiple approaches for ...

Abstract: This paper improves on a noted square-root RTS Kalman smoothing algorithm proposed by Park and Kailath for the application purpose. This improved square-root RTS algorithm is able to ...